The Gamekid: If Isaac has red heart containers, killing four enemies negates the health cost, and killing more results in a net gain of health.Cancer: Repeated uses within the same room cost only half a heart.Other cards such as V - The Hierophant and VI - The Lovers result in no net loss of health and can be used to trigger items that activate upon taking damage. Blank Card: Grants infinite health when combined with XIX - The Sun.File:DLC Indicator.png When used by Keeper, it will only drain one coin heart.Without extra lives, this item is useless when playing as The Lost as a successful use will kill The Lost.If Isaac has less than two black or soul hearts, it will remove them but will not remove any red hearts.If the item has any charges, the Sharp Plug will not work.If Isaac's current activated item has no charges, attempting to activate the item fully recharges it in exchange for two hearts of Isaac's health.
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